What does BUFF stand for?

Big Ugly Fat Fellow - Nickname for B-52 bomber

Brothers United for Future Foreskins (EA)

Buffalo

Buffalo-Bomag - NCIC construction equipment make code (NCIC)

Buffalo National River - Harrison, AR - National Park Service designator (NPSD)

Buffalo, NY - American Association of Railroads railroad junction routing code

Buffer (NASA)

Bufflehead - Common English name - American Ornithologists Union four-character bird identification - Scientific name: Bucephala Albeola (IBP)